- 100 Onwards INR
- White Solid
- 1.6±0.1 g/cm3
Empirical Formula (Hill Notation): C13H10N2O4
Molecular Weight: 258.23
CAS Number: 2614-06-4
|color||white to beige|
|solubility||DMSO: soluble15 mg/mL, clear|
|storage temp.||room temp|
|Gene Information|| human ... LITAF(9516), TNF(7124)|
mouse ... Nos2(18126)
rat ... Nos1(24598)
(-)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor Î± (TNF-Î±). (R)-Thalidomide is called "safe enantiomer", but it can be converted in the body to (S)-isomer.
Thalidomide is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml. It is insoluble in ethanol and water.
Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos.
Features and BenefitsThis compound was developed by Celgene.
- Cash in Advance (CID), Cash Advance (CA)
- 500 KG Per Month
- 2-8 Week
- Sample costs shipping and taxes has to be paid by the buyer
- Carton and Poly Bag.
- Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
- All India
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