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(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate

(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate
(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate
Price And Quantity
  • 1
  • Kilograms/Kilograms
  • 100 INR
Product Specifications
  • C19H26Cl2N2O
  • 405.79 Grams (g)
  • (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate
  • 98%
    Product Description

    (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate

    • Synonym: trans-(1S,2S)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride hydrate

      • Empirical Formula (Hill Notation): C19H26Cl2N2O · HCl · xH2O

      • Molecular Weight: 405.79 (anhydrous basis)

      • CAS Number: 114528-79-9 (anhydrous)

     ssay  


    ≥98% (HPLC)
    form   solid
    optical activity   [α]22/D −36.05°, c = 0.73 in methanol(lit.)
    storage condition   desiccated
    color   white
    solubility   H2O: soluble13 mg/mL
    storage temp.   2-8°C
    Gene Information   human ... OPRK1(4986)

    Description

    Biochem/physiol Actions

    Potent κ opioid receptor agonist; more potent enantiomer of (±)-trans-U-50488.

    Preparation Note

    (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate is soluble in water at 13 mg/ml.

    Application

    (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate (U-50488) has been used as a κ-opioid receptor (KOR) agonist has been used to study its effect on the increase of tidal volumes in adult red-eared slider turtles (Trachemys scripta)[1].

    Features and Benefits

    This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds.
    Trade Information
    • Cash in Advance (CID), Cash Advance (CA)
    • 100 Per Week
    • 1 Week
    • Yes
    • Sample costs shipping and taxes has to be paid by the buyer
    • All India
      Contact Us

      Kesarkunj, Room No. 9, 2 Nd Floor, Vasanji Lalji Road, Kandivali Station Road, Opp. Mcdonlad's, Near Jain Restaurant, Kandivali (West), Mumbai, Maharashtra, 400067, India
      Phone :+918037405224