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NATIONAL ANALYTICAL CORPORATION - CHEMICAL DIVISION

(±)-α-Methyl-(4-tetrazolylphenyl)glycine

(±)-α-Methyl-(4-tetrazolylphenyl)glycine
Product Description

(±)-α-Methyl-(4-tetrazolylphenyl)glycine

    • Empirical Formula (Hill Notation): C10H11N5O2

    • Molecular Weight: 233.23

    • CAS Number: 169209-66-9

 storage temp.  


2-8°C

Description

Biochem/physiol Actions

(±)-α-Methyl-(4-tetrazolylphenyl)glycine (MTPG) was used in rat models of cerebral ischemia to explore the role of group II metabotropic glutamate receptors mGluR2/3 in brain ischemia tolerance. MTPG inhibited the induction of ischemia tolerance indicating the involvement of mGluR2/3 in the induction of the protective mechanism. [1]

Potent antagonist for (1S,3S)-ACPD-sensitive receptors; preference for GluR2 and GluR3 subtypes

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