12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid

12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid
12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid
Price And Quantity
  • 1
  • Kilograms/Kilograms
  • 100 INR
Product Specifications
  • 304.5 Grams (g)
  • C20H32O2
  • −44 °C (−47 °F; 229 K)
  • 0.943 g/cm3
  • 468.9±14.0 °C at 760 mmHg
  • 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid
  • 98%
Product Description

12(S)-Hydroxy-(5z,8z,10e,14z)-Eicosatetraenoic Acid

  • Synonym: (S)-12-HETE

    • Empirical Formula (Hill Notation): c20h32o3

    • Molecular Weight: 320.47

    • Cas Number: 54397-83-0



≥95% (HPLC)


~100 μg/mL In Ethanol

Shipped In  

Dry Ice

Storage Temp.  



Biochem/Physiol Actions

Prometastatic Metabolite Of Arachidonic Acid Via The 12-Lipoxygenase Pathway That Is Expressed In Many Tumor Cell Lines. It Is Produced In Coronary Microvasculature And Is A Potent Inducer Of Relaxation And Hyperpolarization Of These Microvessels. It Activates Large-Conductance Ca2+-Activated K+ Currents In Coronary Microvascular Smooth Muscle.

12(S)-Hete Is A Bioactive Lipid Implicated In Angiogenesis, Growth, And Metastasic Action In Tumor Cell Lines And In Animal Models. Arachidonate 12-Lipoxygenase (12-LOX) Converts Arachidonic Acid To 12(S)-(Hete). Alteration In 12-Lox Expression Or Activity Has Been Reported In Various Carcinomas Including Prostate Carcinoma.


Packaged Under Argon.

Other Notes

Tandem Mass Spectrometry Data Independently Generated By Scripps Center For Metabolomics Is Available To View Or Download In Pdf. H7768.Pdf Tested Metabolites Are Featured On Scripps Center For Metabolomics Metlin Metabolite Database. To Learn More, Visit Sigma.Com/Metlin.

Trade Information
  • Cash in Advance (CID), Cash Advance (CA)
  • 500 Per Month
  • 3-4 Week
  • Yes
  • Sample costs shipping and taxes has to be paid by the buyer
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
  • All India
Contact Us

Kesarkunj, Room No. 9, 2 Nd Floor, Vasanji Lalji Road, Kandivali Station Road, Opp. Mcdonlad's, Near Jain Restaurant, Kandivali (West), Mumbai, Maharashtra, 400067, India
Phone :+918037405224